Canine Genetic Diseases Network
ATTENTION!! We have received notice that the University will be locked down due to the coronavirus situation starting Monday 3/23, thru Sunday 4/12, at least. This means that we will be unable to receive perishable samples during this time.
Our partners at OFA have also suspended taking new orders for DNA tests, due to the uncertainty of when testing may resume. We hope to resume testing April 13th, but that is subject to change as events unfold. The most up-to-date information about University of Missouri operations can be found at the MU Alert webpage: https://mualert.missouri.edu.
If a dog will be unavailable to sample at a later time and it is important to have DNA from that individual, please take a 3-5ml blood sample in EDTA (purple top tubes), freeze it, and hold until further notice. We will resume testing as soon as possible. Sincere apologies for the inconvenience. Please stay safe.
Use the CONTACT US link to send a message – emails will be monitored during this time away from the lab and office. Thank you for understanding.
Researchers at the University of Missouri-Columbia College of Veterinary Medicine and collaborators at several colleges and institutions throughout the country and the world are searching for genetic mutations that cause disease and suffering in dogs. This website is designed to provide information on these projects and serve as a resource for those concerned with canine diseases: breeders, owners, veterinarians, and researchers.
Information presented here is not a substitute for an accurate diagnosis and specific advice geared to your pet's needs. If you suspect your dog has one of the diseases discussed here, we encourage you to have a veterinarian examine the dog and advise you. We also encourage you to participate in the research and help find answers.
DNA Tests Currently Available
Several disease mutations have been identified for inherited diseases in some breeds. See the "DNA TESTS AVAILABLE" section of this website, or click here for a list of DNA-based tests available and testing instructions. Please note that for most diseases, in most breeds, we are still in the research phase, an no test is available at this time. We invite you to participate in the research to help speed discovery of mutations, and make tests available for more diseases. Please see the appropriate disease page for more information, and the forms to participate in research.
October 9, 2017 ANNOUNCEMENT!! Researchers at the University of Missouri, College of Veterinary Medicine and the Animal Health Trust in collaboration with Wisdom Animal Health have found the mutation associated with Spongiform LeukoEncephaloMyelpathy (SLEM), known as "Shaking Puppy" syndrome, in Border Terriers. We are pleased to announce that a DNA test is now available. See Spongiform Leukoencephalomyelopathy section for details.
April 25, 2013 ANNOUNCEMENT!! The Animal Health Trust and the University of Missouri have issued a joint statement regarding the genes identified causing cerebellar ataxia in Jack/Parson Russell Terriers. See Ataxia section for details.
March 20, 2013 ANNOUNCEMENT!! DNA mutation responsible for Canine Multipe System Degeneration (CMSD or PNA) in Kerry Blue Terriers and Chinese Crested Dogs has been identified - test available. See Ataxia section for announcement & testing details, or CLICK HERE to go directly to the announcement with testing information and instructions.
May 14, 2010 ANNOUNCEMENT!! (updated Oct 4, 2010) DNA mutation responsible for Neonatal Cerebellar Ataxia (NCA) in Coton de Tulears has been identified - test available as of May 25, 2010 for Coton de Tulear NCA. See Ataxia section for announcement & testing details, or CLICK HERE to go directly to the announcement with testing information and instructions.
January 28, 2010 ANNOUNCEMENT!! DNA mutation responsible for Neuronal Ceroid Lipofuscinosis (NCL) in Tibetan Terriers has been identified - test available as of February 11, 2009 for Tibetan Terrier NCL through OFA (Orthopedic Foundation for Animals). Dogs sampled during the research, or owners willing to send a blood sample can be tested NOW! See Neuronal Ceroid Lipofuscinosis section for announcement & testing details.
Sept 3, 2009 ANNOUNCEMENT!! DNA mutation responsible for Lens Luxation has been identified - test available NOW for PLL through OFA (Orthopedic Foundation for Animals). See Glaucoma & Lens Luxation section for announcement and testing details.
IMPORTANT ANNOUNCEMENT!! DNA mutation responsible for Degenerative Myelopathy has been identified - test available NOW for DM through OFA (Orthopedic Foundation for Animals). See Degenerative Myelopathy section for details.